When the Buddha fails to achieve reconciliation among quarrelsome bhikkhus at Kosambi, he withdraws into solitude and later encounters an inspiring community of monks devoted to liberation. He teaches them the path of inner purification based on his own practice prior to full awakening—discerning and abandoning eleven subtle impurities of mind, developing collectedness in three ways, and realizing unshakable liberation.

In this discourse, the Buddha advises cultivating the qualities of patience, loving-kindness and compassion. For true character is revealed only when tested by disagreeable words and deeds. Using vivid similes culminating with the simile of the saw, the Buddha instructs to not give rise to a mind of hate, even if bandits were to seize and carve one up limb by limb.

The Buddha shares in poignant terms his observations on the agitation all beings experience which led to his urgency to awaken. He then shares on the path to awakening and describes the dwelling of an awakened being.

The Buddha illustrates that his true inheritance is the Dhamma, not material possessions. Venerable Sāriputta clarifies the practice of seclusion by listing numerous harmful qualities to abandon and the Middle Way that leads to abandoning of them, to clear vision, wisdom, tranquility, to full awakening.

The Buddha uses the simile of a defiled cloth to explain how the mind can be similarly defiled by various impurities, and how it can be purified by abandoning them. And it is through this very practice that one arrives at unshakeable faith in the Buddha, the Dhamma, and the Saṅgha. The Buddha also addresses a brahmin in verses who believes in purification by bathing in river.

The Buddha explains the cause and condition by which a person comes to be recognized as aggressive or gentle. He illuminates how the presence or absence of passion, aversion, and delusion determines whether one is susceptible to provocation and reacts with anger, or remains unshaken.

When a cowherd is murdered shortly after serving the Buddha a meal, the monks report the tragedy. The Buddha responds with an inspired utterance, revealing that a wrongly directed mind inflicts even greater harm on oneself than what an enemy may do to an enemy.

Dhammapada verses 290–305 share on the renunciation of lesser happiness for greater joy, mindfulness of the body, and applying effort to overcome defilements. Further, the verses highlight the harm of neglecting what should be done, consequence of imposing suffering on another, while praising recollection of the Buddha, Dhamma, and Saṅgha as well as the qualities of mindfulness, non-violence, and cultivation. The verses conclude with the benefits of solitude and the wilderness for those who are energetic and self-restrained.

Dhammapada verses 383–423 redefine ‘Brāhmaṇa’ (sage) by inner attainment, not birth or appearance. Through effort, a true sage cuts craving, understands reality, and realizes Nibbāna. Fearless, detached, pure, and restrained, they embody non-violence and patience. Free from defilements and attachments, having overcome suffering and rebirth, the sage achieves the ultimate goal, radiating wisdom and peace.