The Buddha teaches on the six sense bases regarding the arising of suffering (interior), guiding disciples toward discernment of sense experience and release from clinging.

SN 35.21 The Arising of Suffering (Interior)

“Yo, bhikkhave, cakkhussa uppādo ṭhiti abhinibbatti pātubhāvo, dukkhasseso uppādo, rogānaṁ ṭhiti, jarāmaraṇassa pātubhāvo. Yo sotassa …pe… yo ghānassayo jivhāyayo kāyassayo manassa uppādo ṭhiti abhinibbatti pātubhāvo, dukkhasseso uppādo, rogānaṁ ṭhiti, jarāmaraṇassa pātubhāvo.

Yo ca kho, bhikkhave, cakkhussa nirodho vūpasamo atthaṅgamo, dukkhasseso nirodho, rogānaṁ vūpasamo, jarāmaraṇassa atthaṅgamo. Yo sotassayo ghānassayo jivhāyayo kāyassayo manassa nirodho vūpasamo atthaṅgamo, dukkhasseso nirodho, rogānaṁ vūpasamo, jarāmaraṇassa atthaṅgamo”ti.

Navamaṁ.

Reference Translation by Bhikkhu Sujato (CC0).

“Yo, bhikkhave, cakkhussa uppādo ṭhiti abhinibbatti pātubhāvo, dukkhasseso uppādo, rogānaṁ ṭhiti, jarāmaraṇassa pātubhāvo.

“Mendicants, the arising, continuation, and manifestation and regeneration of the eye is the arising of suffering, the continuation of diseases, and the manifestation of old age and death.

Yo sotassa …pe…

The arising, continuation, and manifestation and regeneration of the ear …

yo ghānassa

nose …

yo jivhāya

tongue …

yo kāyassa

body …

yo manassa uppādo ṭhiti abhinibbatti pātubhāvo, dukkhasseso uppādo, rogānaṁ ṭhiti, jarāmaraṇassa pātubhāvo.

and mind is the arising of suffering, the continuation of diseases, and the manifestation of old age and death.

Yo ca kho, bhikkhave, cakkhussa nirodho vūpasamo atthaṅgamo, dukkhasseso nirodho, rogānaṁ vūpasamo, jarāmaraṇassa atthaṅgamo.

The cessation, settling, and disappearance of the eye is the cessation of suffering, the settling of diseases, and the disappearance of old age and death.

Yo sotassa

The cessation, settling, and ending of the ear,

yo ghānassa

nose,

yo jivhāya

tongue,

yo kāyassa

body,

yo manassa nirodho vūpasamo atthaṅgamo, dukkhasseso nirodho, rogānaṁ vūpasamo, jarāmaraṇassa atthaṅgamo”ti.

and mind is the cessation of suffering, the settling of diseases, and the disappearance of old age and death.”

Navamaṁ.

Qualities:

Ending

Ending

The complete exhaustion and ending of craving, aversion, and delusion—the three roots of suffering. It refers to both the gradual wearing away of defilements through practice and the final cessation that constitutes Nibbāna.

Also known as: cessation, exhaustion, gradual ending, wearing away
Pāli: khaya, khīṇa, nirodha
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Suffering

Suffering

Unpleasantness, discontentment, dissatisfaction, stress, pain, disease, i.e. mild or intense suffering that is inherent in conditioned existence.

Also known as: discomfort, unpleasantness, discontentedness, dissatisfaction, stress, pain, disease, distress, affliction
Pāli: dukkha
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Last updated on July 27, 2026