SN 22.142 Suffering (3rd)

A driving ‘thirst’ that reaches out toward experiences, identities, or outcomes as the place to find satisfaction—“if only I had that.” It spins stories of lack, binds the mind to becoming, and invariably leads to suffering.

A wholesome motivation, interest, or objective that acts as the starting point for effort and application of will.

A grasping mental quality of craving, possessiveness, or lustful wanting that clings to objects or experiences; it fuels attachment and obstructs renunciation and contentment

Unpleasantness, discontentment, dissatisfaction, stress, pain, disease, i.e. mild or intense suffering that is inherent in conditioned existence.